Publications HAL des membres

Christian Dina

      2018

    • [1] New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study
      Thierry Le Tourneau, Solena Le Scouarnec, Caroline Cueff, Daniel Bernstein, Jan J. J. Aalberts, Simon Lecointe, Jean Mérot, Jonathan A. Bernstein, Toon Oomen, Christian Dina, Matilde Karakachoff, Hubert Desal, Ousama Al Habash, Francesca N. Delling, Romain Capoulade, Albert J. H. Suurmeijer, David Milan, Russell A. Norris, Roger Markwald, Elena Aikawa, Susan A. Slaugenhaupt, Xavier Jeunemaitre, Albert Hagège, Jean-Christian Roussel, Jean-Noël Trochu, Robert A. Levine, Florence Kyndt, Vincent Probst, Hervé Le Marec, Jean-Jacques Schott.
      https://hal.archives-ouvertes.fr/hal-01833318
    • [3] Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm
      Romain Bourcier, Solena Le Scouarnec, Stephanie Bonnaud, Matilde Karakachoff, Emmanuelle Bourcereau, Sandrine Heurtebise-Chrétien, Céline Menguy, Christian Dina, Floriane Simonet, Alexis Moles, Cédric Lenoble, Pierre Lindenbaum, Stéphanie Chatel, Bertrand Isidor, Emmanuel Génin, Jean-François Deleuze, Jean-Jacques Schott, Hervé Le Marec, Gervaise Loirand, Hubert Desal, Richard Redon, Benjamin Daumas-Duport, Jérôme Connault, Pierre Lebranchu, Thierry Le Tourneau, Pierre Viarouge, Chrisanthi Papagiannaki, Michel Piotin, Hocine Redjem, Mikael Mazighi, Jean-Philippe Desilles, Olivier Naggara, Denis Trystram, Myriam Edjlali-Goujon, Christine Rodriguez, Waghi Ben Hassen, Suzanna Saleme, Charbel Mounayer, Olivier Levrier, Pierre Aguettaz, Xavier Combaz, Anne Pasco, Emeline Berthier, Marc Bintner, Marc Molho, Pascale Gauthier, Cyril Chivot, Vincent Costalat, Cyril Darganzil, Alain Bonafé, Anne Christine Januel, Caterina Michelozzi, Christophe Cognard, Fabrice Bonneville, Philippe Tall, Jean Darcourt, Alessandra Biondi, Cristina Iosif, Elisa Pomero, Jean-Christophe Ferre, Jean Yves Gauvrit, François Eugène, Hélène Raoult, Jean-Christophe Gentric, Julien Ognard, René Anxionnat, Serge Bracard, Anne Laure Derelle, Romain Tonnelet, Laurent Spelle, Léon Ikka, Robert Fahed, Aymeric Rouchaud, Augustin Ozanne, Jildaz Caroff, Nidal Ben Achour, Jacques Moret, Emmanuel Chabert, Jérôme Berge, Gaultier Marnat, Xavier Barreau, Florent Gariel, Frédéric Clarençon, Mohammed Aggour, Fréderic Ricolfi, Adrien Chavent, Pierre Thouant, Pablo Lebidinsky, Brivael Lemogne, Denis Herbreteau, Richard Bibi, Laurent Pierot, Sébastien Soize, Marc Antoine Labeyrie, Christophe Vandendries, Emmanuel Houdart, Appoline Kazemi, Xavier Leclerc, Jean Pierre Pruvo, Sophie Gallas, Stéphane Velasco.
      https://hal.archives-ouvertes.fr/hal-01808225

      2017

    • [4] Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis
      Barbara Schormair, Chen Zhao, Steven Bell, Erik Tilch, Aaro V. Salminen, Benno Pütz, Yves Dauvilliers, Ambra Stefani, Birgit Högl, Werner Poewe, David Kemlink, Karel Sonka, Cornelius G. Bachmann, Walter Paulus, Claudia Trenkwalder, Wolfgang H. Oertel, Magdolna Hornyak, Maris Teder-Laving, Andres Metspalu, Georgios M. Hadjigeorgiou, Olli Polo, Ingo Fietze, Owen A. Ross, Zbigniew Wszolek, Adam S. Butterworth, Nicole Soranzo, Willem H. Ouwehand, David J. Roberts, John Danesh, Richard P. Allen, Christopher J. Earley, William G. Ondo, Lan Xiong, Jacques Montplaisir, Ziv Gan-Or, Markus Perola, Pavel Vodicka, Christian Dina, Andre Franke, Lukas Tittmann, Alexandre F. R. Stewart, Svati H. Shah, Christian Gieger, Annette Peters, Guy A. Rouleau, Klaus Berger, Konrad Oexle, Emanuele Di Angelantonio, David A. Hinds, Bertram Müller-Myhsok, Juliane Winkelmann, 23andme Research Team, Desir Group.
      https://hal.archives-ouvertes.fr/hal-01832985
    • [5] An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
      Robert A. Scott, Laura J. Scott, Reedik Mägi, Letizia Marullo, Kyle J. Gaulton, Marika Kaakinen, Natalia Pervjakova, Tune H. Pers, Andrew D. Johnson, John D. Eicher, Anne U. Jackson, Teresa Ferreira, Yeji Lee, Clement Ma, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Lu Qi, Natalie R. Van Zuydam, Anubha Mahajan, Han Chen, Peter Almgren, Ben F. Voight, Harald Grallert, Martina Müller-Nurasyid, Janina S. Ried, Nigel W. Rayner, Neil Robertson, Lennart C. Karssen, Elisabeth M. Leeuwen, Sara M. Willems, Christian Fuchsberger, Phoenix Kwan, Tanya M. Teslovich, Pritam Chanda, Man Li, Yingchang Lu, Christian Dina, Dorothee Thuillier, Loic Yengo, Longda Jiang, Thomas Sparso, Hans A. Kestler, Himanshu Chheda, Lewin Eisele, Stefan Gustafsson, Mattias Frånberg, Rona J. Strawbridge, Rafn Benediktsson, Astradur B. Hreidarsson, Augustine Kong, Gunnar Sigurðsson, Nicola D. Kerrison, Jian'An Luan, Liming Liang, Thomas Meitinger, Michael Roden, Barbara Thorand, Tõnu Esko, Evelin Mihailov, Caroline Fox, Ching-Ti Liu, Denis Rybin, Bo Isomaa, Valeriya Lyssenko, Tiinamaija Tuomi, David J. Couper, James S. Pankow, Niels Grarup, Christian T. Have, Marit E. Jørgensen, Torben Jørgensen, Allan Linneberg, Marilyn C. Cornelis, Rob M. Dam, David J. Hunter, Peter Kraft, Qi Sun, Sarah Edkins, Katharine R. Owen, John R. B. Perry, Andrew R. Wood, Eleftheria Zeggini, Juan Tajes-Fernandes, Goncalo R. Abecasis, Lori L. Bonnycastle, Peter S. Chines, Heather M. Stringham, Heikki A. Koistinen, Leena Kinnunen, Bengt Sennblad, Thomas W. Mühleisen, Markus M. Nöthen, Sonali Pechlivanis, Damiano Baldassarre, Karl Gertow, Steve E. Humphries, Elena Tremoli, Norman Klopp, Julia Meyer, Gerald Steinbach, Roman Wennauer, Johan G. Eriksson, Satu Mӓnnistö, Leena Peltonen, Emmi Tikkanen, Guillaume Charpentier, Elodie Eury, Stéphane Lobbens, Bruna Gigante, Karin Leander, Olga Mcleod, Erwin P. Bottinger, Omri Gottesman, Douglas Ruderfer, Matthias Blüher, Peter Kovacs, Anke Tonjes, Nisa M. Maruthur, Chiara Scapoli, Raimund Erbel, Karl-Heinz Jöckel, Susanne Moebus, Ulf Faire, Anders Hamsten, Michael Stumvoll, Panagiotis Deloukas, Peter J. Donnelly, Timothy M. Frayling, Andrew T. Hattersley, Samuli Ripatti, Veikko Salomaa, Nancy L. Pedersen, Bernhard O. Boehm, Richard N. Bergman, Francis S. Collins, Karen L. Mohlke, Jaakko Tuomilehto, Torben Hansen, Oluf Pedersen, Inês Barroso, Lars Lannfelt, Erik Ingelsson, Lars Lind, Cecilia M. Lindgren, Stephane Cauchi, Philippe Froguel, Ruth J. F. Loos, Beverley Balkau, Heiner Boeing, Paul W. Franks, Aurelio Barricarte Gurrea, Domenico Palli, Yvonne T. Schouw, David Altshuler, Leif C. Groop, Claudia Langenberg, Nicholas J. Wareham, Eric Sijbrands, Cornelia M. Duijn, Jose C. Florez, James B. Meigs, Eric Boerwinkle, Christian Gieger, Konstantin Strauch, Andres Metspalu, Andrew D. Morris, Colin N. A. Palmer, Frank B. Hu, Unnur Thorsteinsdottir, Kari Stefansson, Josée Dupuis, Andrew P. Morris, Michael Boehnke, Mark I. Mccarthy, Inga Prokopenko, Diabetes Genetics Replication, Meta-Analysis (diagram) Consortium.
      https://hal.archives-ouvertes.fr/hal-01832132
    • [6] An association test to detect clustered disease-risk rare variants
      Elodie Persyn, Matilde Karakachoff, Solena Le Scouarnec, Camille Le Clézio, Dominique Campion, Schott Jean-Jacques, Richard Redon, Lise Bellanger, Christian Dina.
      https://hal.archives-ouvertes.fr/hal-01801793

      2016

    • [7] Dysfunction of the Voltage-Gated K + Channel b2 Subunit in a Familial Case of Brugada Syndrome
      Vincent Portero, Solena Le Scouarnec, Zeineb Es-Salah-Lamoureux, Sophie Burel, Jean-Baptiste Gourraud, Stephanie Bonnaud, Pierre Lindenbaum, Floriane Simonet, Jade Violleau, Estelle Baron, Eleonore Moreau, Carol Scott, Stephanie Chatel, Gildas Loussouarn, Thomas O 'Hara, Philippe Mabo, Christian Dina, Herve Le Marec, Jean-Jacques Schott, Vincent Probst, Isabelle Baro, Céline Marionneau, Flavien Charpentier, Richard Redon.
      http://www.hal.inserm.fr/inserm-01331008
    • [8] Utilizing the Jaccard index to reveal population stratification in sequencing data: a simulation study and an application to the 1000 Genomes Project
      Dmitry Prokopenko, Julian Hecker, Edwin K. Silverman, Marcello Pagano, Markus M. Nöthen, Christian Dina, Christoph Lange, Heide Loehlein Fier.
      https://hal.archives-ouvertes.fr/hal-01831591
    • [9] Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I
      Xavier Daumy, Mohamed-Yassine Amarouch, Pierre Lindenbaum, Stéphanie Bonnaud, Eric Charpentier, Beatrice Bianchi, Sabine Nafzger, Estelle Baron, Swanny Fouchard, Aurélie Thollet, Florence Kyndt, Julien Barc, Solena Le Scouarnec, Naomasa Makita, Hervé Le Marec, Christian Dina, Jean-Baptiste Gourraud, Vincent Probst, Hugues Abriel, Richard Redon, Jean-Jacques Schott.
      https://hal.archives-ouvertes.fr/hal-01831586
    • [10] Search for Rare Copy-Number Variants in Congenital Heart Defects Identifies Novel Candidate Genes and a Potential Role for FOXC1 in Patients With Coarctation of the Aorta
      Marta Sanchez-Castro, Hadja Eldjouzi, Eric Charpentier, Pierre-François Busson, Quentin Hauet, Pierre Lindenbaum, Béatrice Delasalle-Guyomarch, Adrien Baudry, Olivier Pichon, Cécile Pascal, Bruno Lefort, Fanny Bajolle, Philippe Pezard, Jean-Jacques Schott, Christian Dina, Richard Redon, Véronique Gournay, Damien Bonnet, Cédric Le Caignec.
      https://hal.archives-ouvertes.fr/hal-01831746
    • [11] De Novo Truncating Mutations in the kinetochore-microtubules attachment gene CHAMP1 Cause Syndromic Intellectual Disability
      Bertrand Isidor, Sébastien Küry, Jill A. Rosenfeld, Thomas Besnard, Sébastien Schmitt, Shelagh Joss, Sally J. Davies, Robert Roger Lebel, Alex Henderson, Christian P. Schaaf, Haley E. Streff, Yaping Yang, Vani Jain, Nodoka Chida, Xenia Latypova, Cédric Le Caignec, Benjamin Cogné, Sandra Mercier, Marie Vincent, Estelle Colin, Dominique Bonneau, Anne-Sophie Denommé, Philippe Parent, Brigitte Gilbert-Dussardier, Sylvie Odent, Annick Toutain, Amélie Piton, Christian Dina, Audrey Donnart, Pierre Lindenbaum, Eric Charpentier, Richard Redon, Kenji Iemura, Masanori Ikeda, Kozo Tanaka, Stéphane Bézieau.
      https://hal-univ-rennes1.archives-ouvertes.fr/hal-01259225
    • [12] Dysfunction of the Voltage-Gated K+ Channel beta 2 Subunit in a Familial Case of Brugada Syndrome
      Vincent Portero, Solena Le Scouarnec, Zeineb Es-Salah-Lamoureux, Sophie Burel, Jean-Baptiste Gourraud, Stephanie Bonnaud, Pierre Lindenbaum, Floriane Simonet, Jade Violleau, Estelle Baron, Eleonore Moreau, Carol Scott, Stephanie Chatel, Gildas Loussouarn, Thomas O'Hara, Philippe Mabo, Christian Dina, Herve Le Marec, Jean-Jacques Schott, Vincent Probst, Isabelle Baró, Céline Marionneau, Flavien Charpentier, Richard Redon.
      https://hal-univ-rennes1.archives-ouvertes.fr/hal-01414464

      2015

    • [13] Staphylokinase and ABO group phenotype: new players in Staphylococcus aureus implant-associated infections development
      Guillaume Ghislain Aubin, Jean-Philippe Lavigne, Béatrice Guyomarch, Christian Dina, François Gouin, Didier Lepelletier, Stéphane Corvec.
      https://hal.archives-ouvertes.fr/hal-01830597
    • [14] Mitral valve disease−morphology and mechanisms
      Robert A. Levine, Albert A. Hagége, Daniel P. Judge, Muralidhar Padala, Jacob P. Dal-Bianco, Elena Aikawa, Jonathan Beaudoin, Joyce Bischoff, Nabila Bouatia-Naji, Patrick Bruneval, Jonathan T. Butcher, Alain Carpentier, Miguel Chaput, Adrian H. Chester, Catherine Clusel, Francesca N. Delling, Harry C. Dietz, Christian Dina, Ronen Durst, Leticia Fernandez-Friera, Mark D. Handschumacher, Morten O. Jensen, Xavier P. Jeunemaitre, Hervé Le Marec, Thierry Le Tourneau, Roger R. Markwald, Jean Mérot, Emmanuel Messas, David P. Milan, Tui Neri, Russell A. Norris, David Peal, Maelle Perrocheau, Vincent Probst, Michael Pucéat, Nadia Rosenthal, Jorge Solis, Jean-Jacques Schott, Ehud Schwammenthal, Susan A. Slaugenhaupt, Jae-Kwan Song, Magdi H. Yacoub.
      https://hal.archives-ouvertes.fr/hal-01830969
    • [16] Mutations in DCHS1 cause mitral valve prolapse
      Ronen Durst, Kimberly Sauls, David S. Peal, Annemarieke Devlaming, Katelynn Toomer, Maire Leyne, Monica Salani, Michael E. Talkowski, Harrison Brand, Maëlle Perrocheau, Charles Simpson, Christopher Jett, Matthew R. Stone, Florie Charles, Colby Chiang, Stacey N. Lynch, Nabila Bouatia-Naji, Francesca N. Delling, Lisa A. Freed, Christophe Tribouilloy, Thierry Le Tourneau, Hervé Le Marec, Leticia Fernandez-Friera, Jorge Solis, Daniel Trujillano, Stephan Ossowski, Xavier Estivill, Christian Dina, Patrick Bruneval, Adrian Chester, Jean-Jacques Schott, Kenneth D. Irvine, Yaopan Mao, Andy Wessels, Tahirali Motiwala, Michel Puceat, Yoshikazu Tsukasaki, Donald R. Menick, Harinath Kasiganesan, Xingju Nie, Anne-Marie Broome, Katherine Williams, Amanda Johnson, Roger R. Markwald, Xavier Jeunemaitre, Albert Hagege, Robert A. Levine, David J. Milan, Russell A. Norris, Susan A. Slaugenhaupt.
      https://hal.archives-ouvertes.fr/hal-01830584
    • [17] Investigation of the Matrix Metalloproteinase-2 Gene in Patients with Non-Syndromic Mitral Valve Prolapse
      Maëlle Perrocheau, Soto Romuald Kiando, Déwi Vernerey, Christian Dina, Pilar Galan, Albert Hagege, Xavier Jeunemaitre, Nabila Bouatia-Naji.
      https://hal.archives-ouvertes.fr/hal-01830977
    • [18] A Statistical Association Test for the Identification of Clustered Disease Risk Variants
      Elodie Persyn, Matilde Karakachoff, Floriane Simonet, Jean-Jacques Schott, Richard Redon, Lise Bellanger, Christian Dina.
      https://hal.archives-ouvertes.fr/hal-01222285
    • [19] 0210 : Effect of SCN5A mutations and SCN10A, SCN5A and HEY2 frequent variants on ECG of Brugada patients during ajmaline test
      Dylan Therasse, Floriane Simonet, Christian Dina, Aurélie Thollet, Philippe Mabo, Frederic Sacher, Dominique Babuty, Philippe Maury, Jean Jacques Schott, Hervé Le Marec, Richard Redon, Vincent Probst, Jean-Baptiste Gourraud.
      https://hal-univ-rennes1.archives-ouvertes.fr/hal-01150488
    • [20] Testing the burden of rare variation in arrhythmia-susceptibility genes provides new insights into molecular diagnosis for Brugada syndrome
      Solena Le Scouarnec, Matilde Karakachoff, Jean-Baptiste Gourraud, Pierre Lindenbaum, Stéphanie Bonnaud, Vincent Portero, Laetitia Duboscq-Bidot, Xavier Daumy, Floriane Simonet, Raluca Teusan, Estelle Baron, Jade Violleau, Elodie Persyn, Lise Bellanger, Julien Barc, Stéphanie Chatel, Raphael Martins, Philippe Mabo, Frederic Sacher, Michel Haïssaguerre, Florence Kyndt, Sébastien Schmitt, Stéphane Bézieau, Hervé Le Marec, Christian Dina, Jean-Jacques Schott, Vincent Probst, Richard Redon.
      https://hal-univ-rennes1.archives-ouvertes.fr/hal-01201946
    • [21] Genetic association analyses highlight biological pathways underlying mitral valve prolapse
      Christian Dina, Nabila Bouatia-Naji, Nathan Tucker, Francesca N. Delling, Katelynn Toomer, Ronen Durst, Maelle Perrocheau, Leticia Fernandez-Friera, Jorge Solis, Thierry Le Tourneau, Ming-Huei Chen, Vincent Probst, Yohan Bosse, Philippe Pibarot, Diana Zelenika, Mark Lathrop, Serge Hercberg, Ronan Roussel, Emelia J. Benjamin, Fabrice Bonnet, Su Hao Lo, Elena Dolmatova, Floriane Simonet, Simon Lecointe, Florence Kyndt, Richard Redon, Hervé Le Marec, Philippe Froguel, Patrick T. Ellinor, Ramachandran S. Vasan, Patrick Bruneval, Roger R. Markwald, Russell A. Norris, David J. Milan, Susan A. Slaugenhaupt, Robert A. Levine, Jean-Jacques Schott, Albert A. Hagege, Xavier Jeunemaitre.
      https://hal-univ-rennes1.archives-ouvertes.fr/hal-01191656

      2014

    • [22] Rare Variants in Human Genetic Diseases: Comparison of Association Statistical Tests
      Lise Bellanger, Elodie Persyn, Floriane Simonet, Richard Redon, Jean-Jacques Schott, Solena Le Scouarnec, Matilde Karakachoff, Christian Dina.
      https://hal.archives-ouvertes.fr/hal-01037977
    • [23] Statistical tests for Rare Variants Data Rare Variants in Human Genetic Diseases: Comparison of Association Statistical Tests
      Lise Bellanger, Elodie Persyn, Floriane Simonet, Richard Redon, Jean-Jacques Schott, Solena Le Scouarnec, Matilde Karakachoff, Christian Dina.
      https://hal.archives-ouvertes.fr/hal-01160576

      2012

    • [24] Parental electrocardiographic screening identifies a high degree of inheritance for congenital and childhood nonimmune isolated atrioventricular block.
      Alban-Elouen Baruteau, Albin Behaghel, Swanny Fouchard, Philippe Mabo, Jean-Jacques Schott, Christian Dina, Stéphanie Chatel, Elisabeth Villain, Jean-Benoit Thambo, François Marçon, Véronique Gournay, Francis Rouault, Alain Chantepie, Sophie Guillaumont, François Godart, Raphaël P Martins, Béatrice Delasalle, Caroline Bonnet, Alain Fraisse, Jean-Marc Schleich, Jean-René Lusson, Yves Dulac, Jean-Claude Daubert, Hervé Le Marec, Vincent Probst.
      https://hal.archives-ouvertes.fr/hal-00880957
    • [25] Multifocal Ectopic Purkinje-Related Premature Contractions: A New SCN5A-Related Cardiac Channelopathy.
      Gabriel Laurent, Samuel Saal, Mohamed Yassine Amarouch, Delphine Béziau, Roos Marsman, Laurence Faivre, Julien Barc, Christian Dina, Geraldine Bertaux, Olivier Barthez, Christel Thauvin-Robinet, Philippe Charron, Véronique Fressart, Alice Maltret, Elisabeth Villain, Estelle Baron, Jean Mérot, Rodolphe Turpault, Yves Coudière, Flavien Charpentier, Jean-Jacques Schott, Gildas Loussouarn, Arthur Wilde, Jean-Eric Wolf, Isabelle Baró, Florence Kyndt, Vincent Probst.
      http://www.hal.inserm.fr/inserm-00719034

      2010

    • [27] GWAS-AS: assistance for a thorough evaluation of advanced algorithms dedicated to genome-wide association studies
      Thomas Morisseau, Raphaël Mourad, Christian Dina, Philippe Leray, Christine Sinoquet.
      https://hal.archives-ouvertes.fr/hal-00915535

      2009

    • [28] Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
      David Meyre, Jérôme Delplanque, Jean Chèvre, Cécile Lecoeur, Stéphane Lobbens, Sophie Gallina, Emmanuelle Durand, Vincent Vatin, Franck Degraeve, Christine Proença, Stefan Gaget, Antje Körner, Peter Kovacs, Wieland Kiess, Jean Tichet, Michel Marre, Anna-Liisa Hartikainen, Fritz Horber, Natascha Potoczna, Serge Hercberg, Claire Lévy-Marchal, François Pattou, Barbara Heude, Maïthe Tauber, Mark I Mccarthy, Alexandra I F Blakemore, Alexandre Montpetit, Constantin Polychronakos, Jacques Weill, Lachlan J M Coin, Julian Asher, Paul Elliott, Marjo-Riitta Jarvelin, Sophie Visvikis-Siest, Beverley Balkau, Rob Sladek, David Balding, Andrew Walley, Christian Dina, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-01655335

      2008

    • [29] Effects of TCF7L2 polymorphisms on obesity in European populations.
      Stéphane Cauchi, Hélène Choquet, Ruth Gutiérrez-Aguilar, Frédéric Capel, Katrine Grau, Christine Proença, Christian Dina, Alex Duval, Beverley Balkau, Michel Marre, Natascha Potoczna, Dominique Langin, Fritz Horber, Thorkild Sørensen, Guillaume Charpentier, David Meyre, Philippe Froguel.
      http://www.hal.inserm.fr/inserm-00408903

      2007

    • [30] TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis.
      Stéphane Cauchi, Younes El Achhab, Hélène Choquet, Christian Dina, Franz Krempler, Raimund Weitgasser, Chakib Nejjari, Wolfgang Patsch, Mohamed Chikri, David Meyre, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00173654
    • [31] Variation in FTO contributes to childhood obesity and severe adult obesity.
      Christian Dina, David Meyre, Sophie Gallina, Emmanuelle Durand, Antje Körner, Peter Jacobson, Lena M S Carlsson, Wieland Kiess, Vincent Vatin, Cecile Lecoeur, Jérome Delplanque, Emmanuel Vaillant, François Pattou, Juan Ruiz, Jacques Weill, Claire Levy-Marchal, Fritz Horber, Natascha Potoczna, Serge Hercberg, Catherine Le Stunff, Pierre Bougnères, Peter Kovacs, Michel Marre, Beverley Balkau, Stéphane Cauchi, Jean-Claude Chèvre, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00173651
    • [32] A genome-wide association study identifies novel risk loci for type 2 diabetes.
      Robert Sladek, Ghislain Rocheleau, Johan Rung, Christian Dina, Lishuang Shen, David Serre, Philippe Boutin, Daniel Vincent, Alexandre Belisle, Samy Hadjadj, Beverley Balkau, Barbara Heude, Guillaume Charpentier, Thomas J Hudson, Alexandre Montpetit, Alexey V Pshezhetsky, Marc Prentki, Barry I Posner, David J Balding, David Meyre, Constantin Polychronakos, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00173692
    • [33] Comment on "A common genetic variant is associated with adult and childhood obesity".
      Christian Dina, David Meyre, Chantal Samson, Jean Tichet, Michel Marre, Beatrice Jouret, Marie Aline Charles, Beverley Balkau, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00126938

      2006

    • [34] Genotype-by-nutrient interactions assessed in European obese women : A case-only study.
      Jose L Santos, Philippe Boutin, Camilla Verdich, Claus Holst, Lesli H Larsen, Soren Toubro, Christian Dina, Wim Saris, Ellen E Blaak, Johnatan Hoffstedt, Moira A Taylor, Jan Polak, Karine Clement, Dominique Langin, Arne Astrup, Philippe Froguel, Oluf Pedersen, Thorkild I A Sorensen, J Alfredo Martinez.
      https://hal.archives-ouvertes.fr/hal-00126951
    • [35] TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study.
      Stéphane Cauchi, David Meyre, Hélène Choquet, Christian Dina, Catherine Born, Michel Marre, Beverley Balkau, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00126954
    • [36] Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes.
      Stéphane Cauchi, David Meyre, Christian Dina, Hélène Choquet, Chantal Samson, Sophie Gallina, Beverley Balkau, Guillaume Charpentier, François Pattou, Volodymyr Stetsyuk, Raphaël Scharfmann, Bart Staels, Gema Frühbeck, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00173852
    • [37] Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: supportive evidence for linkage at 3p14.
      Bruno Etain, Flavie Mathieu, Marcella Rietschel, Wolfgang Maier, Margot Albus, Patrick Mckeon, S. Roche, Carmel Kealey, Douglas Blackwood, Walter Muir, Franc Bellivier, C. Henry, Christian Dina, Sophie Gallina, H. Gurling, Alain Malafosse, Martin Preisig, François Ferrero, Sven Cichon, J. Schumacher, Stéphanie Ohlraun, M. Borrmann-Hassenbach, Peter Propping, Rami Abou Jamra, Thomas Schulze, Andrej Marusic, Mojca Dernovsek, Bruno Giros, Thomas Bourgeron, Arnaud Lemainque, Delphine Bacq, Christine Betard, Céline Charon, Markus Nöthen, Mark Lathrop, Marion Leboyer.
      http://www.hal.inserm.fr/inserm-00132874
    • [38] Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.
      Thorkild Sørensen, Philippe Boutin, Moira A Taylor, Lesli H Larsen, Camilla Verdich, Liselotte Petersen, Claus Holst, Søren M Echwald, Christian Dina, Søren Toubro, Martin Petersen, Jan Polak, Karine Clément, J Alfredo Martínez, Dominique Langin, Jean-Michel Oppert, Vladimir Stich, Ian Macdonald, Peter Arner, Wim Saris, Oluf Pedersen, Arne Astrup, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174364
    • [39] Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population.
      Martine Vaxillaire, Aurélie Dechaume, Valérie Vasseur-Delannoy, Saida Lahmidi, Vincent Vatin, Frédéric Leprêtre, Philippe Boutin, Serge Hercberg, Guillaume Charpentier, Christian Dina, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174461
    • [40] ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity.
      Nabila Bouatia-Naji, David Meyre, Stéphane Lobbens, Karin Séron, Frédéric Fumeron, Beverley Balkau, Barbara Heude, Béatrice Jouret, Philipp E Scherer, Christian Dina, Jacques Weill, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174464
    • [41] Genetic Polymorphisms and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets
      Thorkild Sørensen, Philippe Boutin, Moira Taylor, Lesli Larsen, Camilla Verdich, Liselotte Petersen, Claus Holst, Søren Echwald, Christian Dina, Søren Toubro, Martin Petersen, Jan Polak, Karine Clément, J. Alfredo Martinez, Dominique Langin, Jean-Michel Oppert, Vladimir Stich, Ian Macdonald, Peter Arner, Wim Saris, Oluf Pedersen, Arne Astrup, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00094684

      2005

    • [42] Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.
      David Meyre, Nabila Bouatia-Naji, Agnès Tounian, Chantal Samson, Cécile Lecoeur, Vincent Vatin, Maya Ghoussaini, Christophe Wachter, Serge Hercberg, Guillaume Charpentier, Wolfgang Patsch, François Pattou, Marie-Aline Charles, Patrick Tounian, Karine Clément, Béatrice Jouret, Jacques Weill, Betty A Maddux, Ira D Goldfine, Andrew Walley, Philippe Boutin, Christian Dina, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174474
    • [43] Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function.
      Bernadette Neve, Martin E Fernandez-Zapico, Vered Ashkenazi-Katalan, Christian Dina, Yasmin H Hamid, Erik Joly, Emmanuel Vaillant, Yamina Benmezroua, Emmanuelle Durand, Nicolas Bakaher, Valerie Delannoy, Martine Vaxillaire, Tiffany Cook, Geesje M Dallinga-Thie, Hans Jansen, Marie-Aline Charles, Karine Clément, Pilar Galan, Serge Hercberg, Nicole Helbecque, Guillaume Charpentier, Marc Prentki, Torben Hansen, Oluf Pedersen, Raul Urrutia, Danielle Melloul, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174488
    • [44] Analysis of sequence variability in the CART gene in relation to obesity in a Caucasian population.
      Audrey Guérardel, Mouna Barat-Houari, Francis Vasseur, Christian Dina, Vincent Vatin, Karine Clément, Delphine Eberlé, Valérie Vasseur-Delannoy, Christopher Bell, Pilar Galan, Serge Hercberg, Nicole Helbecque, Natascha Potoczna, Fritz Horber, Philippe Boutin, Philippe Froguel.
      http://www.hal.inserm.fr/inserm-00090860

      2004

    • [45] Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians.
      Emmanuelle Durand, Philippe Boutin, David Meyre, Marie-Aline Charles, Karine Clement, Christian Dina, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174512
    • [46] Genome-wide linkage analysis for severe obesity in french caucasians finds significant susceptibility locus on chromosome 19q.
      Christopher G Bell, Michael Benzinou, Afshan Siddiq, Cécile Lecoeur, Christian Dina, Arnaud Lemainque, Karine Clément, Arnaud Basdevant, Bernard Guy-Grand, Charles A Mein, David Meyre, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174527
    • [47] A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2.
      David Meyre, Cécile Lecoeur, Jérôme Delplanque, Stephan Francke, Vincent Vatin, Emmanuelle Durand, Jacques Weill, Christian Dina, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174547
    • [48] VNTR polymorphism of the insulin gene and childhood overweight in a general population.
      Barbara Heude, Séverine Dubois, Marie-Aline Charles, Marianne Deweirder, Christian Dina, Jean-Michel Borys, Pierre Ducimetière, Philippe Froguel, Fleurbaix Laventie Ville Santé.
      http://www.hal.inserm.fr/inserm-00086410

      2003

    • [49] GAD2 on chromosome 10p12 is a candidate gene for human obesity.
      Philippe Boutin, Christian Dina, Francis Vasseur, Séverine Dubois, Laetitia Corset, Karin Séron, Lynn Bekris, Janice Cabellon, Bernadette Neve, Valérie Vasseur-Delannoy, Mohamed Chikri, Marie-Aline Charles, Karine Clement, Ake Lernmark, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174549
    • [50] A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes.
      Florence Demenais, Timo Kanninen, Cecilia M Lindgren, Steven Wiltshire, Stéphane Gaget, Candice Dandrieux, Peter Almgren, Marketa Sjögren, Andrew Hattersley, Christian Dina, Tiinamaija Tuomi, Mark I Mccarthy, Philippe Froguel, Leif C Groop.
      https://hal.archives-ouvertes.fr/hal-00174575
    • [51] A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.
      Timothy M Frayling, Cecilia M Lindgren, Jean Claude Chevre, Stephan Menzel, Marie Wishart, Yamina Benmezroua, Alison Brown, Julie C Evans, Pamidghantam Subba Rao, Christian Dina, Cécile Lecoeur, Timo Kanninen, Peter Almgren, Michael P Bulman, Youxiang Wang, James Mills, Rosemarie Wright-Pascoe, Melanie M Mahtani, Francesco Prisco, Angels Costa, Ignacio Cognet, Torben Hansen, Oluf Pedersen, Sian Ellard, Tiinamaija Tuomi, Leif C Groop, Philippe Froguel, Andrew T Hattersley, Martine Vaxillaire.
      https://hal.archives-ouvertes.fr/hal-00174598

      2002

    • [52] A quantitative trait locus influencing type 2 diabetes susceptibility maps to a region on 5q in an extended French family.
      Lisa J Martin, Anthony G Comuzzie, Sophie Dupont, Nathalie Vionnet, Christian Dina, Sophie Gallina, Mouna Houari, John Blangero, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174601
    • [53] Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians.
      Francis Vasseur, Nicole Helbecque, Christian Dina, Stéphane Lobbens, Valérie Delannoy, Stéphane Gaget, Philippe Boutin, Martine Vaxillaire, Frédéric Leprêtre, Sophie Dupont, Kazuo Hara, Karine Clément, Bernard Bihain, Takashi Kadowaki, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174613
    • [54] Positional candidate gene analysis of Lim domain homeobox gene (Isl-1) on chromosome 5q11-q13 in a French morbidly obese population suggests indication for association with type 2 diabetes.
      Mouna Barat-Houari, Karine Clément, Vincent Vatin, Christian Dina, Geneviève Bonhomme, Francis Vasseur, Bernard Guy-Grand, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174719
    • [55] Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p.
      Yasumichi Mori, Shuichi Otabe, Christian Dina, Kazuki Yasuda, Céline Populaire, Cécile Lecoeur, Vincent Vatin, Emmanuelle Durand, Kazuo Hara, Terumasa Okada, Kazuyuki Tobe, Philippe Boutin, Takashi Kadowaki, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-00174723
    • [56] Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.
      Kazuo Hara, Philippe Boutin, Yasumichi Mori, Kazuyuki Tobe, Christian Dina, Kazuki Yasuda, Toshimasa Yamauchi, Shuichi Otabe, Terumasa Okada, Kazuhiro Eto, Hiroko Kadowaki, Ryoko Hagura, Yasuo Akanuma, Yoshio Yazaki, Ryozo Nagai, Matsuo Taniyama, Koichi Matsubara, Madoka Yoda, Yasuko Nakano, Motowo Tomita, Satoshi Kimura, Chikako Ito, Philippe Froguel, Takashi Kadowaki.
      https://hal.archives-ouvertes.fr/hal-00174757
    • [57] Genetic, pharmacological and functional analysis of cholecystokinin-1 and cholecystokinin-2 receptor polymorphism in type 2 diabetes and obese patients.
      Sophie Marchal-Victorion, Nathalie Vionnet, Chantal Escrieut, Frédérique Dematos, Christian Dina, Marlène Dufresne, Nicole Vaysse, Lucien Pradayrol, Philippe Froguel, Daniel Fourmy.
      https://hal.archives-ouvertes.fr/hal-00174758

      2000

    • [58] Genomewide Search for Type 2 Diabetes–Susceptibility Genes in French Whites: Evidence for a Novel Susceptibility Locus for Early-Onset Diabetes on Chromosome 3q27-qter and Independent Replication of a Type 2–Diabetes Locus on Chromosome 1q21–q24
      Nathalie Vionnet, El Habib Hani, Sophie Dupont, Sophie Gallina, Stephan Francke, Sébastien Dotte, Frédérique De Matos, Emmanuelle Durand, Frédéric Leprêtre, Cécile Lecoeur, Philippe Gallina, Lirije Zekiri, Christian Dina, Philippe Froguel.
      https://hal.archives-ouvertes.fr/hal-01655341
page

Groupement de Recherche en Intégration de données Omics à Très grande Echelle